RUNX1-ETO deregulates the proliferation and growth factor responsiveness of human hematopoietic progenitor cells downstream of the myeloid transcription factor, MYCT1

Leukemia. 2012 Jan;26(1):177-9. doi: 10.1038/leu.2011.188. Epub 2011 Jul 29.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cell Proliferation*
  • Core Binding Factor Alpha 2 Subunit / physiology*
  • Hematopoietic Stem Cells / physiology*
  • Humans
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Nuclear Proteins / physiology*
  • Proto-Oncogene Proteins / physiology*
  • RUNX1 Translocation Partner 1 Protein
  • Recombinant Fusion Proteins / metabolism
  • Transcription Factors / physiology*

Substances

  • Core Binding Factor Alpha 2 Subunit
  • Intercellular Signaling Peptides and Proteins
  • MYCT1 protein, human
  • Nuclear Proteins
  • Proto-Oncogene Proteins
  • RUNX1 Translocation Partner 1 Protein
  • RUNX1 protein, human
  • RUNX1T1 protein, human
  • Recombinant Fusion Proteins
  • Transcription Factors