Facilitative glucose transporters: an expanding family

Trends Biochem Sci. 1990 Jan;15(1):18-23. doi: 10.1016/0968-0004(90)90125-u.


The uptake of glucose into most eukaryotic cells is accomplished by a carrier-mediated transport system, facilitative diffusion, which transports glucose down its chemical gradient in a stereospecific manner. Recent studies have shown that facilitative transport of glucose across the plasma membrane is mediated by a family of structurally related proteins. This review summarizes the structural and functional features of the family of facilitative glucose transporters.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Diabetes Mellitus / metabolism
  • Glucose / metabolism*
  • Humans
  • Molecular Sequence Data
  • Monosaccharide Transport Proteins / metabolism*
  • Protein Conformation


  • Monosaccharide Transport Proteins
  • Glucose