Predictors of pneumococcal co-infection for patients with pandemic (H1N1) 2009

Emerg Infect Dis. 2011 Aug;17(8):1475-8. doi: 10.3201/eid1708.101673.

Abstract

We conducted a systematic investigation of pneumococcal co-infection in patients with a diagnosis of pandemic (H1N1) 2009 and any risk factor for complications or with severity criteria. We found 14% prevalence, with one third of patients having nonpneumonic infections. A severity assessment score >1 and high C-reactive protein levels were predictors of pneumococcal co-infection.

MeSH terms

  • Adolescent
  • Adult
  • C-Reactive Protein / analysis*
  • Coinfection / epidemiology*
  • Coinfection / microbiology
  • Coinfection / virology
  • Humans
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza, Human / complications*
  • Influenza, Human / diagnosis
  • Influenza, Human / epidemiology*
  • Influenza, Human / physiopathology
  • Pandemics*
  • Pneumococcal Infections / complications*
  • Pneumococcal Infections / diagnosis
  • Pneumococcal Infections / epidemiology*
  • Pneumococcal Infections / microbiology
  • Prevalence
  • Risk Factors
  • Severity of Illness Index
  • Spain / epidemiology
  • Streptococcus pneumoniae / immunology
  • Streptococcus pneumoniae / isolation & purification
  • Young Adult

Substances

  • C-Reactive Protein