Targeted therapies: Using β-blockers to inhibit breast cancer progression

Nat Rev Clin Oncol. 2011 Aug 2;8(9):511-2. doi: 10.1038/nrclinonc.2011.123.


Three recent population studies have translated laboratory investigations into a clinical setting and concur in presenting evidence that suggest a dramatic new role for β-blockers in reducing metastases, tumor recurrence and specific mortality in breast cancer. Should we be skeptical about these controversial findings?

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adrenergic beta-Antagonists / pharmacology*
  • Adrenergic beta-Antagonists / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / mortality*
  • Female
  • Humans


  • Adrenergic beta-Antagonists