Endogenous ocular nocardiosis: an interventional case report with a review of the literature

Surv Ophthalmol. Sep-Oct 2011;56(5):383-415. doi: 10.1016/j.survophthal.2011.03.003. Epub 2011 Aug 2.

Abstract

We present an illustrative case of endogenous ocular Nocardia (EON) infection in a man with Hodgkin disease treated by chemotherapy who underwent aggressive vitreoretinal surgery for diagnosis and treatment of a subretinal abscess. Visual acuity recovered from hand movements to 20/25. We review the 38 reported cases of EON published between 1967 and 2007, describe the clinical presentation from a systemic and ocular point of view, examine which ocular procedures were successful in identifying the bacterium, and analyze ocular morbidity and the factors affecting successful treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abscess / diagnosis
  • Abscess / drug therapy
  • Abscess / microbiology*
  • Aged
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Fatal Outcome
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Nocardia / isolation & purification*
  • Nocardia Infections / diagnosis
  • Nocardia Infections / drug therapy
  • Nocardia Infections / microbiology*
  • Retinal Diseases / diagnosis
  • Retinal Diseases / drug therapy
  • Retinal Diseases / microbiology*
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Trimethoprim, Sulfamethoxazole Drug Combination