GeneXpert--a Game-Changer for Tuberculosis Control?

PLoS Med. 2011 Jul;8(7):e1001064. doi: 10.1371/journal.pmed.1001064. Epub 2011 Jul 26.

Abstract

Carlton Evans considers whether the new tuberculosis diagnostic test, GeneXpert, is the solution for TB control that it's said to be.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Antibiotics, Antitubercular / pharmacology
  • DNA, Bacterial / analysis
  • DNA, Bacterial / genetics
  • Diagnostic Tests, Routine / instrumentation
  • Diagnostic Tests, Routine / methods*
  • Drug Resistance, Bacterial / drug effects
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Mycobacterium tuberculosis / classification
  • Mycobacterium tuberculosis / drug effects
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification*
  • Nucleic Acid Amplification Techniques / methods*
  • Point-of-Care Systems
  • Rifampin / pharmacology
  • Sensitivity and Specificity
  • Tuberculosis / diagnosis*
  • Tuberculosis / microbiology
  • Tuberculosis, Multidrug-Resistant / complications
  • Tuberculosis, Multidrug-Resistant / diagnosis*
  • Tuberculosis, Multidrug-Resistant / microbiology
  • Tuberculosis, Pulmonary / complications
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / microbiology

Substances

  • Antibiotics, Antitubercular
  • DNA, Bacterial
  • Rifampin