Traumatic cerebrospinal fluid leaks

Otolaryngol Clin North Am. 2011 Aug;44(4):857-73, vii. doi: 10.1016/j.otc.2011.06.007.

Abstract

This article discusses the epidemiology, diagnosis, and management of traumatic cerebrospinal fluid (CSF) leaks. An overview of traumatic CSF leaks is presented, and both conservative and operative therapies are reviewed. Management decisions are discussed based on the current literature. Controversial clinical topics are addressed, including the use of prophylactic antibiotics and the timing of surgical repair.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antibiotic Prophylaxis
  • Cerebrospinal Fluid / metabolism
  • Cerebrospinal Fluid Rhinorrhea* / diagnosis
  • Cerebrospinal Fluid Rhinorrhea* / metabolism
  • Cerebrospinal Fluid Rhinorrhea* / physiopathology
  • Cerebrospinal Fluid Rhinorrhea* / surgery
  • Early Medical Intervention
  • Endoscopy* / adverse effects
  • Endoscopy* / methods
  • Humans
  • Meningitis* / etiology
  • Meningitis* / prevention & control
  • Patient Positioning / methods*
  • Postoperative Care
  • Skull Base / injuries
  • Skull Base / pathology
  • Tomography, X-Ray Computed
  • Transferrin / metabolism*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Transferrin