Subcellular localization of casein kinase I

Biochem Biophys Res Commun. 1990 Mar 16;167(2):471-6. doi: 10.1016/0006-291x(90)92047-4.

Abstract

An anti-yeast CKI antiserum was shown to cross-react with CKI isolated from Krebs II mouse ascites tumour cells. The mammalian CKI showed virtually the same molecular mass (app. 45 kDa) as the yeast enzyme. By immunofluorescence it could be shown that CKI is preferably located in the nucleolus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies / isolation & purification
  • Carcinoma, Krebs 2 / enzymology
  • Casein Kinases
  • Cell Line
  • Chromatography, Affinity
  • Fluorescent Antibody Technique
  • Glioma
  • Humans
  • Immunoassay
  • Mice
  • Molecular Weight
  • Protein Kinases / analysis*
  • Protein Kinases / immunology
  • Protein Kinases / isolation & purification
  • Saccharomyces cerevisiae / enzymology
  • Tumor Cells, Cultured / enzymology

Substances

  • Antibodies
  • Protein Kinases
  • Casein Kinases