Pregnancies in perinatally HIV-infected young women and implications for care and service programs

J Assoc Nurses AIDS Care. 2012 Jan-Feb;23(1):41-51. doi: 10.1016/j.jana.2011.05.008. Epub 2011 Aug 4.


A cohort of individuals with perinatally acquired HIV is maturing into reproductive age. This study describes pregnancy incidence and outcomes among females ages 15-25 with perinatally acquired HIV infection receiving comprehensive family-centered services in New York City. Chart reviews from 1998-2006 indicated 33 pregnancies among 96 young women. Twenty-six percent of the cohort experienced a pregnancy during the study period, with a rate of 125 per 1,000 person years in 2006. The age of first pregnancy ranged from 15-25; 24% were younger than 18. Fourteen pregnancies (42%) were terminated. Nineteen pregnancies resulted in live births, and all infants tested negative for HIV. The success of preventing vertical HIV transmission is attributed to interdisciplinary family-centered services, including reproductive health education, family planning, obstetric-gynecologic services and psychosocial support. Such approach is most likely to be effective at promoting healthy reproductive decisions and reducing morbidity in perinatally infected mothers and their children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • HIV Infections / physiopathology*
  • HIV Infections / therapy
  • HIV Infections / transmission
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious / physiopathology*
  • Pregnancy Complications, Infectious / therapy