SEOM clinical guidelines for diagnosis and treatment of testicular seminoma (2010)

Clin Transl Oncol. 2011 Aug;13(8):560-4. doi: 10.1007/s12094-011-0697-7.


Testicular cancer represents the most common malignancy in males aged 15-34 years. Nearly 40% of cases correspond to seminomas and three quarters of them are diagnosed with stage I disease. After orchiectomy, clinical staging should include serial tumour marker assays (alphafetoprotein must be negative), abdominal CT scan and chest X-ray films. Patients with stage I disease can be followedup (active surveillance) or receive adjuvant carboplatin chemotherapy (those with rete testis invasion or non-compliant with follow-up). More advanced disease (stage II and III) and patients with extragonadal seminomas should receive chemotherapy (3-4 courses of BEP) according to IGCCCG risk classification. Residual lesions must be managed by surveillance if they are smaller than 3 cm, while those larger than 3 cm should be evaluated by means of PET. Surgery is only recommended in PET-positive lesions.

Publication types

  • Practice Guideline

MeSH terms

  • Adolescent
  • Adult
  • Humans
  • Male
  • Medical Oncology / methods*
  • Neoplasm Staging / methods
  • Seminoma / therapy*
  • Societies, Medical
  • Testicular Neoplasms / therapy*
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • X-Rays