The role of platelet-rich plasma in rotator cuff repair

Sports Med Arthrosc Rev. 2011 Sep;19(3):244-50. doi: 10.1097/JSA.0b013e318227b2dc.


The shoulder is a common source of disability resulting from traumatic and degenerate tears of the rotator cuff, subacromial impingement, and osteoarthritis. Nonoperative management has focused on treatment of the predisposing factors, the use of analgesics and anti-inflammatory medication usually in association with local anesthetic and steroid injections. Surgical intervention allows debridement of the degenerate cuff and partial thickness cuff tears, subacromial bursitis, impinging bone spurs and osteophytes together with rotator cuff repairs. Repairs of degenerate and torn tissue are often prone to failure due to many intrinsic and extrinsic factors. It is assumed that some biological therapies might improve clinical, mechanical, and histologic outcomes. Injections of platelet-rich plasma (PRP) have led to reduced pain and improved recovery in other degenerate pathologies areas together with the restoration of function. This study reviews the current literature on PRP and in particular discusses its relevance in the treatment of rotator cuff tears.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Therapy*
  • Female
  • Humans
  • Male
  • Platelet-Rich Plasma*
  • Range of Motion, Articular
  • Rats
  • Rotator Cuff / diagnostic imaging
  • Rotator Cuff Injuries*
  • Shoulder Joint / diagnostic imaging
  • Shoulder Joint / injuries
  • Tendon Injuries / diagnostic imaging
  • Tendon Injuries / therapy*
  • Treatment Outcome
  • Ultrasonography
  • Wound Healing