Diffuse pulmonary infiltrates in the immunocompromised host

Clin Chest Med. 1990 Mar;11(1):55-64.


Diffuse pulmonary infiltrates in the immunocompromised host in the majority represent an opportunistic infection. However, in about 25 to 30%, they represent complications of an adverse drug reaction, recurrence of the underlying disease such as leukemia or lymphoma involving the lung, or an idiopathic "fibrosis," and in a small percentage are attributable to an "unrelated" process such as congestive heart failure, pulmonary emboli, community-acquired pneumonia, and so on. In 10 to 20% of the patients, two or more of these processes occur. A pulmonary process in the immunocompromised patient is almost always fatal unless the clinician intervenes with the proper diagnosis and/or effective empiric therapy.

Publication types

  • Review

MeSH terms

  • Humans
  • Immune Tolerance*
  • Lung Diseases / chemically induced
  • Lung Diseases / etiology
  • Lung Diseases / immunology*
  • Opportunistic Infections / immunology
  • Pulmonary Fibrosis / chemically induced
  • Pulmonary Fibrosis / immunology
  • Recurrence