Dissemination of an NDM-2-producing Acinetobacter baumannii clone in an Israeli rehabilitation center

Antimicrob Agents Chemother. 2011 Nov;55(11):5396-8. doi: 10.1128/AAC.00679-11. Epub 2011 Aug 8.

Abstract

New Delhi metallo-β-lactamase (NDM-1) was initially identified in various Enterobacteriaceae and recently in Acinetobacter baumannii. This study described the clonal dissemination of an NDM-2-producing A. baumannii isolate in an Israeli rehabilitation ward and the genetic surroundings of the gene. The bla(NDM-2) gene was surrounded by the ble and trpF genes downstream and two copies of the ISAba125 on both sides. These are the first NDM-producing A. baumannii strains in Israel from patients with no previous travel or hospitalization on the Indian subcontinent.

MeSH terms

  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / enzymology*
  • Acinetobacter baumannii / genetics
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics*
  • Israel
  • Microbial Sensitivity Tests
  • Multiplex Polymerase Chain Reaction
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • beta-Lactamases