The possible roles of brain pericytes in brain ischemia and stroke
- PMID: 21830084
- DOI: 10.1007/s10571-011-9747-5
The possible roles of brain pericytes in brain ischemia and stroke
Abstract
Brain pericytes regulate a variety of functions, such as microcirculation, angiogenesis, and the blood brain barrier in the brain. Recent studies have also shown that they are pluripotent in a manner similar to mesenchymal stem cells. Since, brain pericytes actively control these functions, these cells probably play an important role not only during brain ischemia, but also in the post-stroke period.
Similar articles
-
Pericytes in Brain Injury and Repair After Ischemic Stroke.Transl Stroke Res. 2017 Apr;8(2):107-121. doi: 10.1007/s12975-016-0504-4. Epub 2016 Nov 12. Transl Stroke Res. 2017. PMID: 27837475 Free PMC article. Review.
-
Diverse functions of pericytes in cerebral blood flow regulation and ischemia.J Cereb Blood Flow Metab. 2015 Jun;35(6):883-7. doi: 10.1038/jcbfm.2015.60. Epub 2015 Apr 8. J Cereb Blood Flow Metab. 2015. PMID: 25853910 Free PMC article. Review.
-
MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes.FASEB J. 2018 Jun;32(6):3133-3148. doi: 10.1096/fj.201701121R. Epub 2018 Jan 18. FASEB J. 2018. PMID: 29401609
-
Roles of Pericytes in Stroke Pathogenesis.Cell Transplant. 2018 Dec;27(12):1798-1808. doi: 10.1177/0963689718768455. Epub 2018 May 30. Cell Transplant. 2018. PMID: 29845887 Free PMC article. Review.
-
Effect of Pericytes on Cerebral Microvasculature at Different Time Points of Stroke.Biomed Res Int. 2021 Dec 22;2021:5281182. doi: 10.1155/2021/5281182. eCollection 2021. Biomed Res Int. 2021. PMID: 34977241 Free PMC article. Review.
Cited by
-
Pericyte contractility controls endothelial cell cycle progression and sprouting: insights into angiogenic switch mechanics.Am J Physiol Cell Physiol. 2014 Nov 1;307(9):C878-92. doi: 10.1152/ajpcell.00185.2014. Epub 2014 Aug 20. Am J Physiol Cell Physiol. 2014. PMID: 25143350 Free PMC article.
-
The peripheral immune response after stroke-A double edge sword for blood-brain barrier integrity.CNS Neurosci Ther. 2018 Dec;24(12):1115-1128. doi: 10.1111/cns.13081. Epub 2018 Nov 1. CNS Neurosci Ther. 2018. PMID: 30387323 Free PMC article. Review.
-
The Transcriptional Landscape of Pericytes in Acute Ischemic Stroke.Transl Stroke Res. 2024 Aug;15(4):714-728. doi: 10.1007/s12975-023-01169-x. Epub 2023 Jun 28. Transl Stroke Res. 2024. PMID: 37378751 Free PMC article.
-
Pericyte-derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion.Brain Pathol. 2018 Jul;28(4):521-535. doi: 10.1111/bpa.12523. Epub 2017 May 31. Brain Pathol. 2018. PMID: 28470822 Free PMC article.
-
Diverse Functions and Mechanisms of Pericytes in Ischemic Stroke.Curr Neuropharmacol. 2017;15(6):892-905. doi: 10.2174/1570159X15666170112170226. Curr Neuropharmacol. 2017. PMID: 28088914 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
