Structure predictions of membrane proteins are not that bad

Trends Biochem Sci. 1990 Mar;15(3):93-5. doi: 10.1016/0968-0004(90)90188-h.

Abstract

A simple generalization of the well-known hydrophobicity analysis is sufficient to predict membrane-spanning amphiphilic alpha-helices and beta-strands. The use of this method is illustrated for bacteriorhodopsin, OmpA protein and the photosynthetic reaction centre.

MeSH terms

  • Amino Acid Sequence
  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Bacteriorhodopsins
  • Membrane Proteins*
  • Methods
  • Photosynthetic Reaction Center Complex Proteins
  • Protein Conformation
  • Reproducibility of Results

Substances

  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Membrane Proteins
  • Photosynthetic Reaction Center Complex Proteins
  • Bacteriorhodopsins