Effect of 3-month yoga on oxidative stress in type 2 diabetes with or without complications: a controlled clinical trial

Diabetes Care. 2011 Oct;34(10):2208-10. doi: 10.2337/dc10-2430. Epub 2011 Aug 11.

Abstract

Objective: To assess the effect of yoga on anthropometry, blood pressure, glycemic control, and oxidative stress in type 2 diabetic patients on standard care in comparison with standard care alone.

Research design and methods: The study involved 123 patients stratified according to groups with microvascular complications, macrovascular complications, and peripheral neuropathy and without complications and assigned to receive either standard care or standard care along with additional yoga for 3 months.

Results: In comparison with standard care alone, yoga resulted in significant reduction in BMI, glycemic control, and malondialdehyde and increase in glutathione and vitamin C. There were no differences in waist circumference, waist-to-hip ratio, blood pressure, vitamin E, or superoxide dismutase in the yoga group at follow-up.

Conclusions: Yoga can be used as an effective therapy in reducing oxidative stress in type 2 diabetes. Yoga in addition to standard care helps reduce BMI and improve glycemic control in type 2 diabetic patients.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Ascorbic Acid / blood
  • Blood Glucose / physiology
  • Blood Pressure / physiology
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / therapy*
  • Female
  • Glutathione / blood
  • Glycated Hemoglobin / metabolism
  • Humans
  • Male
  • Malondialdehyde / blood
  • Middle Aged
  • Oxidative Stress / physiology*
  • Superoxide Dismutase / blood
  • Vitamin E / blood
  • Yoga*

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • Vitamin E
  • Malondialdehyde
  • Superoxide Dismutase
  • Glutathione
  • Ascorbic Acid