Irritable bowel syndrome and psychiatric illness

Am J Psychiatry. 1990 May;147(5):565-72. doi: 10.1176/ajp.147.5.565.


Psychiatric illnesses such as mood, anxiety, and somatization disorders share many common features with irritable bowel syndrome. The authors review recent developments in the definition of irritable bowel syndrome and its relationship to psychiatric illness, discuss the diagnostic validity of irritable bowel syndrome from several perspectives, and offer a pathophysiological model of irritable bowel syndrome that integrates many of the biological and psychosocial findings of earlier studies. Psychiatric evaluation appears to be an important factor in the diagnosis and treatment of patients with irritable bowel syndrome.

Publication types

  • Review

MeSH terms

  • Colonic Diseases, Functional / complications
  • Colonic Diseases, Functional / diagnosis*
  • Colonic Diseases, Functional / physiopathology
  • Diagnosis, Differential
  • Humans
  • Locus Coeruleus / physiopathology
  • Mental Disorders / complications
  • Mental Disorders / diagnosis*
  • Mental Disorders / physiopathology
  • Models, Biological