A Myxococcus xanthus bacterial tyrosine kinase, BtkA, is required for the formation of mature spores

Yoshio Kimura; Shinji Yamashita; Yumi Mori; Yuki Kitajima; Kaoru Takegawa

doi:10.1128/JB.05750-11

A Myxococcus xanthus bacterial tyrosine kinase, BtkA, is required for the formation of mature spores

J Bacteriol. 2011 Oct;193(20):5853-7. doi: 10.1128/JB.05750-11. Epub 2011 Aug 12.

Authors

Yoshio Kimura¹, Shinji Yamashita, Yumi Mori, Yuki Kitajima, Kaoru Takegawa

Affiliation

¹ Department of Applied Biological Science, Faculty of Agriculture, Kagawa University, Miki-cho, Kagawa, Japan. kimura@ag.kagawa-u.ac.jp

Abstract

A Myxococcus xanthus cytoplasmic bacterial tyrosine kinase, BtkA, showed phosphorylation activity in the presence of Exo. Phosphorylated BtkA was expressed late after starvation induction and early after glycerol induction. The btkA mutant was unable to complete maturation to heat- and sonication-resistant spores under both starvation- and glycerol-induced developmental conditions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Bacterial Proteins / chemistry
Bacterial Proteins / genetics
Bacterial Proteins / metabolism*
Glycerol / metabolism
Hot Temperature
Molecular Sequence Data
Myxococcus xanthus / chemistry
Myxococcus xanthus / enzymology*
Myxococcus xanthus / genetics
Myxococcus xanthus / growth & development
Protein-Tyrosine Kinases / chemistry
Protein-Tyrosine Kinases / genetics
Protein-Tyrosine Kinases / metabolism*
Sequence Alignment
Spores, Bacterial / growth & development*

Substances

Bacterial Proteins
Protein-Tyrosine Kinases
Glycerol