[Alkaloids and anthraquinones from branches and leaves of uvaria kurzii]

Zhongguo Zhong Yao Za Zhi. 2011 May;36(9):1190-2.
[Article in Chinese]

Abstract

Objective: To investigate the chemical constituents of the branches and leaves of Uvaria kurzii.

Method: The compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatographic methods. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data.

Result: Nine compounds were isolated and identified as: bidebiline A(1), annobraine (2), oxoputerine (3), atherospermidine (4), liriodenine (5), physcion (6), questin (7), rubiadin 3-methyl ether (8), emodin (9).

Conclusion: Compound 1-4, 6-9 were isolated from the genus Uvaria for the first time. Compound 3-5 showed inhabitation activities against tumor cell lines A549, Bel7402, BGC823, HCT-8, A2780, respectively.

MeSH terms

  • Alkaloids / chemistry*
  • Anthraquinones / chemistry*
  • Aporphines / chemistry
  • Emodin / analogs & derivatives
  • Emodin / chemistry
  • Magnetic Resonance Spectroscopy
  • Plant Leaves / chemistry*
  • Plant Stems / chemistry*
  • Uvaria / chemistry*

Substances

  • Alkaloids
  • Anthraquinones
  • Aporphines
  • questin
  • atherospermidine
  • rubiadin
  • liriodenine
  • physcione
  • Emodin