Covalent coercion by Legionella pneumophila

Cell Host Microbe. 2011 Aug 18;10(2):89-91. doi: 10.1016/j.chom.2011.08.002.

Abstract

Adenylylation of Rab proteins appears to be an intriguing mechanism that Legionella pneumophila uses to modulate their activity during infection. Now the reverse reaction (deadenylylation) (Neunuebel et al., 2011; Tan and Luo, 2011) and a new posttranslational modification (phosphocholination) of Rab1 (Mukherjee et al., 2011) have been reported.

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