The pharmacology and therapeutics of diuretics in the pediatric patient

Pediatr Clin North Am. 1990 Apr;37(2):463-504. doi: 10.1016/s0031-3955(16)36880-8.


Selection of appropriate diuretic therapy in children is hampered by a lack of age-specific pharmacokinetic and pharmacodynamic data, especially in premature neonates. Well-designed clinical trials in neonates, infants, and younger children are necessary prerequisites to safer and more efficacious diuretic therapy.

Publication types

  • Review

MeSH terms

  • Child
  • Diuretics / pharmacokinetics
  • Diuretics / pharmacology*
  • Diuretics / therapeutic use
  • Humans
  • Infant
  • Infant, Newborn
  • Kidney / anatomy & histology
  • Kidney / embryology
  • Kidney / physiology


  • Diuretics