Shifting paradigm on Bacillus thuringiensis toxin and a natural model for Enterococcus faecalis septicemia

mBio. 2011 Aug 16;2(4):e00161-11. doi: 10.1128/mBio.00161-11. Print 2011.


The Bt toxin is widely used in agriculture both as a spray and in transgenic plants, yet its precise mode of action against lepidopterans is poorly understood. The study by Mason et al. [mBio 2(3):e00065-11, 2011] revealed that Bt toxin enables an inhabitant of the midgut, Enterococcus faecalis, to enter the hemolymph of larvae and cause septicemia, leading to death.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bacterial Translocation*
  • Enterococcus faecalis / growth & development*
  • Enterococcus faecalis / pathogenicity*
  • Manduca / microbiology*