A T-2 translational research perspective on interventions to improve post-fracture osteoporosis care

Osteoporos Int. 2011 Aug;22 Suppl 3:471-6. doi: 10.1007/s00198-011-1700-4. Epub 2011 Aug 17.


The objectives of this paper are to: quickly outline the extent of the care gap in osteoporosis; define T-2 (knowledge) translation and its relationship to quality improvement; discuss the barriers to best practice in osteoporosis care after a fracture; convey the importance of rigor in design and evaluation of translational interventions by drawing upon examples from the broader literature; describe in some detail a series of post-fracture intervention trials conducted in Alberta, Canada; and make some conclusions specifically about osteoporosis interventions and more generally about T-2 translational research.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Hip Fractures / etiology
  • Humans
  • Middle Aged
  • Osteoporosis / complications
  • Osteoporosis / diagnosis
  • Osteoporosis / therapy*
  • Osteoporotic Fractures / prevention & control*
  • Quality Improvement / organization & administration
  • Randomized Controlled Trials as Topic
  • Translational Research, Biomedical / methods*
  • Wrist Injuries / etiology