Inverse association between fruit, legume, and cereal fiber and the risk of metabolic syndrome: Tehran Lipid and Glucose Study

Diabetes Res Clin Pract. 2011 Nov;94(2):276-83. doi: 10.1016/j.diabres.2011.07.020.


Aims: To evaluate the association between total dietary fiber and its types and sources with the risk of MetS.

Methods: This population-based cross-sectional study was conducted on a representative sample of 2457 adults (1327 male and 1130 female), aged 19-84 years. Dietary intake was assessed using a validated semiquantitative food-frequency questionnaire. Anthropometrics, blood pressure, and fasting blood glucose and lipids were measured according to standard protocols. The MetS was defined according to definition by Adult Treatment Panel III.

Results: Multivariate-adjusted odds ratio of MetS between highest and lowest quartiles was 0.53 (95% CI: 0.39-0.74; P for trend <0.05) for total dietary fiber, 0.60 (0.43-0.84; P for trend <0.05) for soluble fiber, and 0.51 (0.35-0.72; P for trend <0.05) for insoluble fiber. Among sources of dietary fiber, fruit fiber (OR: 0.51; 95% CI: 0.37-0.72), cereal fiber (0.74; 0.57-0.97), and legume fiber (0.73; 0.53-0.99) were inversely associated with the risk of MetS, after adjustment for confounding factors. Intake of vegetable fiber and nut fiber were unrelated to the risk of MetS.

Conclusions: Total dietary fiber, soluble- and insoluble fiber, fruit fiber, cereal fiber and legume fiber were associated with a protective effect for the presence of MetS among this Tehranian population.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Blood Glucose / analysis*
  • Blood Pressure
  • Chi-Square Distribution
  • Cross-Sectional Studies
  • Diet*
  • Dietary Fiber / administration & dosage*
  • Edible Grain*
  • Fabaceae*
  • Female
  • Fruit*
  • Humans
  • Iran / epidemiology
  • Lipids / blood*
  • Logistic Models
  • Male
  • Metabolic Syndrome / blood
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / epidemiology*
  • Metabolic Syndrome / physiopathology
  • Metabolic Syndrome / prevention & control
  • Middle Aged
  • Odds Ratio
  • Prospective Studies
  • Risk Assessment
  • Risk Factors
  • Young Adult


  • Blood Glucose
  • Dietary Fiber
  • Lipids