Neuromodulation is a process of inhibition, stimulation, modification and regulation or therapeutic alteration of activity, electrically and chemically in the peripheral, central or autonomic nervous systems. Direct electric current or electric field alternates the function of nervous system. Coupling the human organism with the Earth directly or via a wire conductor changes the electric potential not only on the surface of the body but also inside it, changing the potential of electric environment of the human organism. Earthing refers to a direct contact with the Earth with bare feet or contact with the Earth with the use of conductive wire attached to the human body during sleeping, or daily activities. During earthing this electric potential equals to electric potential of the Earth and the value of it depends on location, time, atmospheric conditions, moisture of the surface of the Earth. The earthing which changes the density of negative charge in electric environment of the human body influences physiological processes. Our medical hypothesis states that contact with the Earth (earthing) directly or via a conductive wire plays role as a neuromodulative factor, probably primary, which enables the nervous system to be better adapted to the demands of organism and ambient environment. It helps to restore natural, electrical status of the electrical environment of the organism and thus the nervous system. Earthing generates immediate changes in electroencephalography (EEG), surface electromyography (SEMG), and somato-sensory evoked potentials (SSEPs). We hypothesize that earthing through its complex action on bioelectrical environment of human organism and alternations in electrolyte concentrations regulates correct functioning of the nervous system. Earthing significantly influences on the electrical activity of the brain.
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