Donation after cardiac death in pediatric organ transplantation

Curr Opin Organ Transplant. 2011 Oct;16(5):483-8. doi: 10.1097/MOT.0b013e32834a8bf5.

Abstract

Purpose of review: The purpose of this review is to describe the history, current practice, and outcomes of the transplantation of organs donated after cardiac death (DCD) in children.

Recent findings: The rate of death on the waiting list is greater for children under 5 years of age than for any other age group. The organ shortage experienced by the general population awaiting transplantation is made more complex due to the need for size-appropriate organs for transplantation into small children. Pediatric DCD organ recovery has been proposed as a means of ameliorating this shortage.

Summary: The use of DCD organs has experienced resurgence in the past 15 years, and a growing body of literature supports their use in selected cases. Recent experience in pediatric transplantation using DCD heart, lung, liver, and kidney is reviewed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Child
  • Death*
  • Donor Selection / organization & administration*
  • Humans
  • Organ Transplantation / methods*
  • Waiting Lists*