Full-length sequence of a novel HLA-B*15:220 allele identified in an individual from Guadeloupe

Tissue Antigens. 2012 Jan;79(1):75-6. doi: 10.1111/j.1399-0039.2011.01762.x. Epub 2011 Aug 22.

Abstract

The new HLA-B*15:220 allele shows a single-nucleotide substitution in exon 1 at position 47 (C>T) when compared to its closest allele HLA-B*15:03:01, resulting in an amino acid substitution from Ala to Val in the signal peptide at codon -9.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Substitution*
  • Exons / genetics*
  • Guadeloupe
  • HLA-B Antigens / genetics*
  • Humans
  • Mutation, Missense*

Substances

  • HLA-B Antigens