Invasive aspergillosis complicating pandemic influenza A (H1N1) infection in severely immunocompromised patients

Clin Infect Dis. 2011 Sep;53(6):e16-9. doi: 10.1093/cid/cir485.


We report 5 cases of invasive aspergillosis occurring in severely immunosuppressed patients hospitalized with pandemic influenza A (H1N1). We suggest that infection with influenza A (H1N1) may predispose immunocompromised patients to develop invasive aspergillosis. Physicians should be aware of this potential association to allow early diagnosis and prompt treatment of aspergillosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aspergillosis / immunology*
  • Aspergillosis / microbiology
  • Aspergillosis / virology*
  • Disease Outbreaks
  • Fatal Outcome
  • Female
  • Humans
  • Immunocompromised Host*
  • Influenza A Virus, H1N1 Subtype*
  • Influenza, Human / immunology*
  • Influenza, Human / microbiology*
  • Influenza, Human / virology
  • Leukemia, Myeloid, Acute / immunology
  • Liver Transplantation / immunology
  • Male
  • Middle Aged