The efficacy of Ankaferd Blood Stopper for the management of bleeding following total thyroidectomy

J Invest Surg. 2011;24(5):205-10. doi: 10.3109/08941939.2011.586092.


Purpose: Postoperative hematoma remains an uncommon but potentially life-threaten complication of thyroid surgery. The aim of this study is to assess the efficacy of Ankaferd Blood Stopper (ABS) in comparison to hemostasis by conventional technique (HCT) for the controlling of oozing-type bleeding following total thyroidectomy.

Methods: We randomized 61 patients with benign euthyroid multinodular goiter who underwent total thyroidectomy subject to one of the two different hemostasis techniques. There were 31 patients in the HCT group and 30 patients in the ABS group. The study was designed prospectively to compare ABS and HCT groups in terms of operation time, postoperative drainage, duration of postoperative stay, and complications.

Results: Mean postoperative drainage from the closed suction drains at first 24 hr were 24.6 ± 8.6 ml and 12.0 ± 9.2 ml (p = .001) and mean total postoperative drainage were 38.5 ± 13.2 ml and 20.6 ± 12.2 ml (p = .001) in the HCT and ABS groups, respectively, indicating statistically significant differences.

Conclusions: On the basis of the results of this trial, the use of ABS seems to be more effective than HCT to control hemorrhage following total thyroidectomy.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Female
  • Goiter, Nodular / surgery
  • Hematoma / prevention & control
  • Hemostasis, Surgical / methods*
  • Humans
  • Male
  • Middle Aged
  • Plant Extracts / therapeutic use*
  • Postoperative Complications / prevention & control
  • Postoperative Hemorrhage / prevention & control
  • Thyroidectomy / methods


  • Plant Extracts
  • ankaferd blood stopper