Design of a special interpreter for the classification of human chromosomes

L Vanderheydt; A Oosterlinck; H Van Den Berghe

doi:10.1109/tpami.1979.4766908

Design of a special interpreter for the classification of human chromosomes

IEEE Trans Pattern Anal Mach Intell. 1979 Feb;1(2):214-24. doi: 10.1109/tpami.1979.4766908.

Authors

L Vanderheydt¹, A Oosterlinck, H Van Den Berghe

Affiliation

¹ Division of Human Genetics, Department of Human Biology, Minderbroederstraat 12, Leuven, Belgium.

PMID: 21868851
DOI: 10.1109/tpami.1979.4766908

Abstract

The use of new staining methods and the large amount of investigations for human chromosomes has created a need for a useful automated chromosome analysis. Because of the lack of accuracy of the existing systems, a new approach is given. The problems in the different stages of the classification process are described. A comparison of the decision-statistical, syntactical, and interpretative approach is discussed. A system realization for the total karyotyping of chromosomes, based on the interpretative approach, is described in more detail. Guided by one of the models in the world model structure, a current description is recognized in a three-phase interpreter.