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Review
. 2011 Dec;9(12):1044-9.
doi: 10.1016/j.cgh.2011.08.014. Epub 2011 Aug 24.

Treating Clostridium Difficile Infection With Fecal Microbiota Transplantation

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Free PMC article
Review

Treating Clostridium Difficile Infection With Fecal Microbiota Transplantation

Johan S Bakken et al. Clin Gastroenterol Hepatol. .
Free PMC article

Abstract

Clostridium difficile infection is increasing in incidence, severity, and mortality. Treatment options are limited and appear to be losing efficacy. Recurrent disease is especially challenging; extended treatment with oral vancomycin is becoming increasingly common but is expensive. Fecal microbiota transplantation is safe, inexpensive, and effective; according to case and small series reports, about 90% of patients are cured. We discuss the rationale, methods, and use of fecal microbiota transplantation.

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