Effects on transcription of mutations in ygjD, yeaZ, and yjeE genes, which are involved in a universal tRNA modification in Escherichia coli

J Bacteriol. 2011 Nov;193(21):6075-9. doi: 10.1128/JB.05733-11. Epub 2011 Aug 26.


The Escherichia coli ygjD gene is critical for the universal tRNA modification N(6)-threonylcarbamoyladenosine, together with two other essential genes, yeaZ and yjeE. This study showed that the transcription of the thr and ilv operons in ygjD mutants was increased through the inhibition of transcription attenuation and that dnaG transcription was reduced.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Escherichia coli / genetics*
  • Escherichia coli / metabolism
  • Escherichia coli Proteins / genetics*
  • Mutation*
  • RNA, Transfer / metabolism*
  • Transcription, Genetic*


  • Escherichia coli Proteins
  • YeaZ protein, E coli
  • YgjD protein, E coli
  • YjeE protein, E coli
  • RNA, Transfer