Measuring SeHCAT retention: a technical note

Nucl Med Commun. 2011 Oct;32(10):960-6. doi: 10.1097/MNM.0b013e32834a36af.


TauroH-23-((75)Se)selena-25-homocholic acid (SeHCAT) retention has been used for the diagnosis of bile acid malabsorption since the early 1980s. Bile acid malabsorption has been increasingly recognized as an important cause of severe chronic diarroea with subsequent increase in the number of referrals for the SeHCAT test. In this study, we review and discuss the standard techniques for the measurement of SeHCAT retention and describe a simple and modified technique using a noncollimated whole-body scanner, suitable for most modern dual-headed cameras.

Publication types

  • Review

MeSH terms

  • Humans
  • Reproducibility of Results
  • Taurocholic Acid / analogs & derivatives*
  • Taurocholic Acid / pharmacokinetics
  • Whole Body Imaging / instrumentation
  • Whole Body Imaging / methods*


  • Taurocholic Acid
  • 23-seleno-25-homotaurocholic acid