Twenty-four-hour repeatability of diurnal intraocular pressure patterns in glaucomatous and ocular hypertensive individuals

Clinics (Sao Paulo). 2011;66(7):1235-6. doi: 10.1590/s1807-59322011000700019.

Abstract

Objective: To verify the 24-hour repeatability of diurnal intraocular pressure patterns in glaucomatous and ocular hypertensive individuals.

Methods: A prospective analysis of 88 eyes from 88 ocular hypertensive or open-angle glaucoma patients was conducted on diurnal tension curves obtained by the same examiner on two consecutive days. The intraclass correlation coefficient test was used for statistical analysis.

Results: Eighty-eight eyes from 88 patients were analyzed. Fifty-seven patients (64.8%) were female. The mean age of all participants was 68.7 (SD 10.8, range 51-79) years. The intraclass correlation coefficient values for measurements at 8 AM, 11 AM, 2 PM, and 4 PM were 0.80, 0.82, 0.83, and 0.86, respectively (all intraclass correlation coefficient values, p<0.001).

Conclusion: Diurnal intraocular pressure data collected on a single day characterize the diurnal intraocular pressure variability over 24 hours in primary open-angle glaucoma and ocular hypertensive patients.

MeSH terms

  • Aged
  • Circadian Rhythm / physiology*
  • Eye / physiopathology
  • Female
  • Glaucoma / physiopathology
  • Humans
  • Intraocular Pressure / physiology*
  • Male
  • Middle Aged
  • Ocular Hypertension / physiopathology*
  • Prospective Studies
  • Reproducibility of Results
  • Time Factors