The pathway to wisdom is a crooked one. Doctors have many opportunities to become wiser, and may do so in different ways and to different degrees. We suggest several means to facilitate their passage. There remains an additional key step. Seeking wisdom should become embedded in the culture of medicine. This may follow from the types of activities discussed above. We believe that wisdom is underrecognized as a life goal for medical practitioners and teachers. It is the pinnacle that every doctor should strive to achieve.