The miR-10 microRNA precursor family

RNA Biol. Sep-Oct 2011;8(5):728-34. doi: 10.4161/rna.8.5.16324. Epub 2011 Sep 1.

Abstract

The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox gene developmental regulators. Here, we review the current knowledge of the evolution, physiological function and involvement in cancer of this family of microRNAs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Gene Expression Regulation, Developmental
  • Genes, Homeobox
  • Humans
  • MicroRNAs / genetics*
  • Neoplasms / genetics*
  • RNA, Long Noncoding / genetics
  • Transcription Factors / genetics

Substances

  • HOTAIR long untranslated RNA, human
  • MIRN10 microRNA, human
  • MIRN100 microRNA, human
  • MicroRNAs
  • RNA, Long Noncoding
  • Transcription Factors