Invasive Group B Streptococcal Infections in Adults, France (2007-2010)

Clin Microbiol Infect. 2011 Oct;17(10):1587-9. doi: 10.1111/j.1469-0691.2011.03628.x. Epub 2011 Aug 29.

Abstract

Group B streptococcus (GBS) has emerged as an important cause of invasive infection in adults. Here, we report the clinical and microbiological characteristics of 401 non-redundant GBS strains causing adult invasive infections collected during a 4-year period (2007-2010). Bacteraemia without focus (43.4%) and bone and joint infections (18.7%) were the main clinical manifestations. The distribution of capsular polysaccharide (CPS) type showed that types Ia, III, and V accounted for 71.8% of all strains. Resistance to erythromycin increased from 20.2% in 2007 to 35.3% in 2010, and was mainly associated with CPS type V harbouring the erm(B) resistant determinant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bacteremia / epidemiology
  • Bacteremia / microbiology
  • Bacterial Capsules / analysis
  • Bone and Bones / microbiology
  • Drug Resistance, Bacterial
  • Erythromycin / pharmacology
  • Female
  • France / epidemiology
  • Genes, Bacterial
  • Humans
  • Joints / microbiology
  • Male
  • Middle Aged
  • Phenotype
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / microbiology*
  • Streptococcus agalactiae / drug effects
  • Streptococcus agalactiae / genetics
  • Streptococcus agalactiae / pathogenicity*
  • Young Adult

Substances

  • capsular polysaccharide, streptoccal group B type V
  • Erythromycin