Pseudomonas septicaemia after endoscopic retrograde cholangiopancreatography--an unresolved problem

S Afr Med J. 1990 May 19;77(10):509-11.


Over a 6-month period 5 patients with obstructive jaundice developed Gram-negative septicaemia, all within 48 hours of undergoing endoscopic retrograde cholangiopancreatography. The sepsis proved fatal in 3 patients, despite prompt decompression of the obstructed biliary system. In all cases the organism responsible was Pseudomonas aeruginosa and the source of infection appeared to be a contaminated water-bottle attached to the endoscopic apparatus. This report highlights the importance of disinfection techniques and reviews the present situation in respect of antibiotic prophylaxis.

Publication types

  • Review

MeSH terms

  • Aged
  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pseudomonas Infections / etiology*
  • Sepsis / etiology*