What's wrong with correlative experiments?

Nat Cell Biol. 2011 Sep 2;13(9):1011. doi: 10.1038/ncb2325.


Here, we make a case for multivariate measurements in cell biology with minimal perturbation. We discuss how correlative data can identify cause-effect relationships in cellular pathways with potentially greater accuracy than conventional perturbation studies.

MeSH terms

  • Animals
  • Cell Biology / trends*
  • Humans
  • Models, Biological*
  • Signal Transduction*