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Primary Adrenal Leiomyosarcoma: A Case Report and Literature Review

Case Reports

Primary Adrenal Leiomyosarcoma: A Case Report and Literature Review

Mencoboni M et al. Clin Med Oncol.


The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site.PRIMARY LEIOMYOSARCOMA OF THE ADRENAL GLAND IS A VERY RARE MALIGNANT MESENCHYMAL NEOPLASM: to our knowledge, this is only the twelfth case reported in literature.We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.


Figure 1
Figure 1
Gross appearance of the roundish, fibrous neoplasia. Insert: neoplasia with fascicular growth pattern (E.E. 40×).
Figure 2
Figure 2
(A) Positive Desmin immunostaining (20x); (B) Positive Muscle Specific Actin immunostaining (40×).

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