Pulmonary complications following bone marrow transplantation

Clin Chest Med. 1990 Jun;11(2):323-32.


Pulmonary complications are a common cause of morbidity and mortality after bone marrow transplantation. Some of these complications are infectious and related to the degree of ongoing immunosuppression, and thus vary with the posttransplant marrow reconstitution and the need for continued immunomodulating drugs. Noninfectious complications are related to previous chemotherapy, the transplantation protocol and conditioning regimen, and, in allogeneic transplants, the presence of graft-versus-host disease. The various complications are classified based on their timing after the transplant procedure. A diagnostic and therapeutic approach is outlined and the prognosis is discussed.

Publication types

  • Review

MeSH terms

  • Bone Marrow Transplantation / adverse effects*
  • Bone Marrow Transplantation / immunology
  • Graft vs Host Disease / etiology
  • Humans
  • Immune Tolerance
  • Lung Diseases / diagnosis
  • Lung Diseases / drug therapy
  • Lung Diseases / etiology*
  • Opportunistic Infections / etiology
  • Postoperative Complications / etiology