Socioeconomic Position, Stage of Lung Cancer and Time Between Referral and Diagnosis in Denmark, 2001-2008

Br J Cancer. 2011 Sep 27;105(7):1042-8. doi: 10.1038/bjc.2011.342. Epub 2011 Sep 6.

Abstract

Introduction: We investigated the association between socioeconomic position, stage at diagnosis, and length of period between referral and diagnosis in a nationwide cohort of lung cancer patients.

Methods: Through the Danish Lung Cancer Register, we identified 18,103 persons diagnosed with lung cancer (small cell and non-small cell) in Denmark, 2001-2008, and obtained information on socioeconomic position and comorbidity from nationwide administrative registries. The odds ratio (OR) for a diagnosis of advanced-stage lung cancer (stages IIIB-IV) and for a diagnosis >28 days after referral were analysed by multivariate logistic regression models.

Results: The adjusted OR for advanced-stage lung cancer was reduced among persons with higher education (OR, 0.92; 95% confidence interval (CI), 0.84-0.99), was increased in persons living alone (OR, 1.06; 95% CI, 1.01-1.13) and decreased stepwise with increasing comorbidity. Higher education was associated with a reduced OR for >28 days between referral and diagnosis as was high income in early-stage patients. Male gender, age and severe comorbidity were associated with increased ORs in advanced-stage patients.

Interpretation: Differences by socioeconomic position in stage at diagnosis and in the period between referral and diagnosis indicate that vulnerable patients presenting with lung cancer symptoms require special attention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Non-Small-Cell Lung / diagnosis
  • Carcinoma, Non-Small-Cell Lung / mortality
  • Carcinoma, Non-Small-Cell Lung / psychology
  • Denmark
  • Female
  • Follow-Up Studies
  • Health Services Accessibility*
  • Healthcare Disparities*
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / mortality*
  • Lung Neoplasms / psychology
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Referral and Consultation*
  • Risk Factors
  • Small Cell Lung Carcinoma / diagnosis
  • Small Cell Lung Carcinoma / mortality
  • Small Cell Lung Carcinoma / psychology
  • Socioeconomic Factors*
  • Survival Rate
  • Time Factors