Silver catalyzed intramolecular cyclization for synthesis of 3-alkylideneoxindoles via C-H functionalization

Chem Commun (Camb). 2011 Oct 28;47(40):11336-8. doi: 10.1039/c1cc14394h. Epub 2011 Sep 6.

Abstract

A novel protocol for the preparation of various 3-alkylideneoxindoles via a silver-catalyzed aromatic C-H functionalization has been developed. The process is simple, environmentally conscious, and avoids the use of abundant bases, oxidants, or other additives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry*
  • Catalysis
  • Cyclization
  • Hydrogen / chemistry*
  • Indoles / chemical synthesis*
  • Indoles / chemistry*
  • Silver / chemistry*
  • Stereoisomerism
  • Substrate Specificity

Substances

  • Indoles
  • Silver
  • Carbon
  • Hydrogen