"Acquired" adrenal hyperplasia with 21-hydroxylase deficiency is not the same genetic disorders as congenital adrenal hyperplasia

J Clin Endocrinol Metab. 1979 Feb;48(2):356-9. doi: 10.1210/jcem-48-2-356.

Abstract

Hormonal studies and HLA genotyping were performed on the family of a patient with "acquired" adrenal hyperplasia (AAH) due to 21-hydroxylase deficiency. The results of these studies suggest that "AAH", is not the same genetic disease as CAH.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adrenal Glands / pathology*
  • Adrenal Hyperplasia, Congenital*
  • Adrenocortical Hyperfunction / blood*
  • Adrenocortical Hyperfunction / genetics
  • Adrenocortical Hyperfunction / immunology
  • Adrenocorticotropic Hormone
  • Androstenedione / blood
  • Dehydroepiandrosterone / blood
  • Female
  • Histocompatibility Antigens / analysis
  • Humans
  • Hydrocortisone / blood
  • Hydroxyprogesterones / blood
  • Hyperplasia
  • Steroid Hydroxylases / deficiency*
  • Testosterone / blood

Substances

  • Histocompatibility Antigens
  • Hydroxyprogesterones
  • Testosterone
  • Androstenedione
  • Dehydroepiandrosterone
  • Adrenocorticotropic Hormone
  • Steroid Hydroxylases
  • Hydrocortisone