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Review
. 2011 Sep;23(9):479-92.
doi: 10.1111/j.1745-7599.2011.00665.x.

Interpreting Clinical Trial Results for Moderate-To-Severe Rheumatoid Arthritis: Practical Applications for Rheumatology Healthcare Providers

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Review

Interpreting Clinical Trial Results for Moderate-To-Severe Rheumatoid Arthritis: Practical Applications for Rheumatology Healthcare Providers

Nicole Furfaro et al. J Am Acad Nurse Pract. .

Abstract

Purpose: To provide a general overview of clinical trials and more specifically define measurements common to rheumatoid arthritis clinical trials for the purpose of providing a foundation for rheumatology healthcare providers to translate clinical trial findings into their clinical practice and enhance their patient education discussions.

Data sources: English-language publications cited in the MEDLINE database were used to develop the content of this review article.

Conclusions: The role of rheumatology healthcare providers has evolved to include numerous vital functions, such as expanding communication between specialists and primary care providers, patient education and counseling, assistance with coping strategies, monitoring response to therapy, and administration of therapy. Education regarding clinical trial design, rationale, and discussion of endpoints has not been strongly emphasized for rheumatology healthcare providers who are increasingly introduced to novel agents and need to assimilate findings from clinical trials into daily practice.

Implications for practice: Familiarity with the basics of clinical trial design and efficacy endpoints of new rheumatoid arthritis therapeutics, translation and application of that knowledge into daily practice, and the ability to explain this information with patients will further enhance the ability of the rheumatology healthcare provider to optimize care for their patients with rheumatoid arthritis.

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