What are candidate biobehavioral mechanisms underlying the association between secondhand smoke exposure and mental health?

Med Hypotheses. 2011 Dec;77(6):1009-10. doi: 10.1016/j.mehy.2011.08.036. Epub 2011 Sep 7.


There is a consistent positive and significant association between secondhand smoke exposure and mental health outcomes in the literature. There are potential genetic and behavioral confounders (e.g., psychological stress, maternal depression, and family functioning) were discussed, as well as potential causal neurobiological pathways (e.g., dopamine system). Further neurobiological research to establish causal pathways is needed as well as the integration of positive observational findings into clinical and public health prevention practices.

MeSH terms

  • Dopamine / metabolism
  • Humans
  • Mental Disorders / chemically induced*
  • Mental Disorders / epidemiology*
  • Models, Psychological*
  • Risk Factors
  • Tobacco Smoke Pollution / adverse effects*


  • Tobacco Smoke Pollution
  • Dopamine