[Effectiveness of scalp cooling in chemotherapy]

Bull Cancer. 2011 Oct;98(9):1119-29. doi: 10.1684/bdc.2011.1430.
[Article in French]


The main objectives of this literature review are to determine if scalp cooling is efficient and safe, if there are side effects and if the patients' quality of life improves. In terms of effectiveness, scalp cooling seems to get good performance in its aim to prevent hair loss in patients receiving chemotherapy. The weighted average results of all identified studies indicate that this technology allows for 63.5% of patients to have a good preservation of their hair. In studies with a group of control, the weighted rates of good preservation of the hair are 50.6% with scalp cooling and 16.3% without. From the standpoint of safety technology, the main risk is that of scalp metastases. However, no study has successfully demonstrated a statistically significant difference between groups of patients receiving chemotherapy with or without scalp cooling.

Publication types

  • Review

MeSH terms

  • Alopecia / chemically induced
  • Alopecia / prevention & control*
  • Antineoplastic Agents / adverse effects*
  • Contraindications
  • Head Protective Devices
  • Humans
  • Hypothermia, Induced / adverse effects
  • Hypothermia, Induced / instrumentation
  • Hypothermia, Induced / methods*
  • Randomized Controlled Trials as Topic
  • Scalp*


  • Antineoplastic Agents