Off-track takes Frizzled off the canonical path

EMBO J. 2011 Sep 14;30(18):3665-6. doi: 10.1038/emboj.2011.311.

Abstract

This issue of The EMBO Journal features the functional characterization of Off-track/PTK7 as a new Wnt co-receptor that determines the biological outcome of cellular Wnt-responses.

Publication types

  • Comment

MeSH terms

  • Animals
  • Drosophila Proteins / metabolism*
  • Gene Expression Regulation, Developmental*
  • Glycoproteins / metabolism*
  • Protein Interaction Mapping*
  • Receptor Protein-Tyrosine Kinases / metabolism*
  • Signal Transduction*
  • Wnt Proteins / metabolism*

Substances

  • Drosophila Proteins
  • Glycoproteins
  • Wnt Proteins
  • Wnt4 protein, Drosophila
  • Otk protein, Drosophila
  • PTK7 protein, Xenopus
  • Receptor Protein-Tyrosine Kinases