Abstract
Two carbapenem-resistant Klebsiella pneumoniae isolates producing the plasmid-encoded carbapenem-hydrolyzing OXA-48 were identified. These isolates, recovered from two patients hospitalized in two different hospitals in Tunisia in December 2010, were not clonally related. Molecular investigations showed that both isolates co-produced the narrow-spectrum β-lactamases TEM-1 and SHV-1, together with the extended-spectrum β-lactamase CTX--15.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / metabolism*
-
Carbapenems / metabolism*
-
Humans
-
Klebsiella Infections / microbiology*
-
Klebsiella pneumoniae / enzymology*
-
Klebsiella pneumoniae / genetics
-
Klebsiella pneumoniae / isolation & purification*
-
Microbial Sensitivity Tests
-
Plasmids
-
Tunisia
-
Urine / microbiology
-
beta-Lactamases / genetics
-
beta-Lactamases / metabolism*
Substances
-
Anti-Bacterial Agents
-
Carbapenems
-
beta-lactamase CTX-M-15
-
beta-lactamase PIT-2
-
beta-Lactamases
-
beta-lactamase TEM-1
-
oxacillinase