Granuloma faciale with subglottic eosinophilic angiocentric fibrosis: case report and review of the literature

Cutis. 2011 Aug;88(2):77-82.

Abstract

Granuloma faciale (GF) is an uncommon inflammatory dermatosis that usually presents on the face as reddish brown or violaceous papules and nodules that may coalesce into plaques. Eosinophilic angiocentric fibrosis (EAF) is a rare fibrosing condition that shares many histologic characteristics with GF and is regarded by some authors as a mucosal counterpart of GF. We present a case of GF with concurrent EAF in a subglottic location with excellent response to an intralesional corticosteroid on the GF lesion, CO2 laser on the EAF lesion, and oral dapsone treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Dapsone / therapeutic use
  • Eosinophilia / diagnosis
  • Eosinophilia / pathology*
  • Eosinophilia / therapy
  • Facial Dermatoses / diagnosis
  • Facial Dermatoses / pathology*
  • Facial Dermatoses / therapy
  • Fibrosis
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Granuloma / diagnosis
  • Granuloma / pathology*
  • Granuloma / therapy
  • Humans
  • Injections, Intralesional
  • Larynx / pathology
  • Lasers, Gas / therapeutic use
  • Male
  • Nose / pathology

Substances

  • Glucocorticoids
  • Dapsone